[xx] Osteomyelitis
Osteo: bone
myel: bone marrow.
itis: inflammation
Symptoms
-Inflammation(mostly S. Aureus) through the blood stream, Fever, weakness
Diagnosis
- complete blood count (CBC)
* increased WBC(Leukocytosis: 감염이니까 당연히 WBC 올라가겠지)
* increased Erythrocyte sedimentation rate (ESR)
* Increased C-reaction protein (CRP)
- X-ray
* thickening of the cortical bone & periosteum
* elevation of the periosteum
* loss of the normal architecture (especially trabecular architecture)
* osteopenia (loss of bone mass) -> evident when > half of bone matrix is destroyed.
-Bone scan or MRI to confirm the presence of osteomyelitis and identify an abscess.
-Bone biopsy to identify the pathogen and confirm the diagnosis.
Tx
-Antibiotics
-if there's an abscess -> surgery.
-surgery needed to remove any necrotic bone